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The Geschwind Lab
The Geschwind laboratory is working to improve our understanding of human neuropsychiatric diseases, such as autism and neurodegenerative diseases, and their relationship to the range of normal human higher cognitive function. We use a combination of genetic, functional genomic and neurobiological methods in our work--frequently in collaboration with other laboratories or disciplines. Our methodological focus involves the application of network analyses and systems biology, which offer the promise of integration of multiple levels of data, connecting molecular pathways to nervous system function in health and disease.

image courtesy of Mitch Tobias, UCLA Medicine MagazineDr. Daniel Geschwind is the Gordon and Virginia MacDonald Distinguished Chair in Human Genetics and is a professor of neurology and psychiatry at the UCLA School of Medicine. He is director of the Neurogenetics Program and the Center for Autism Research and Treatment (CART) and co-director of the Center for Neurobehavioral Genetics at UCLA. Dr. Geschwind obtained an A.B. in psychology and chemistry at Dartmouth College and his M.D./Ph.D. at Yale School of Medicine prior to completing his internship, residency, and postdoctoral fellowship at UCLA. He joined the UCLA faculty in 1997.
In addition to his research, Dr. Geschwind is active on the scientific advisory boards of The Faculty of 1000 Medicine, Autism Speaks, and the NIMH Scientific Advisory Council. He received the Derek Denny-Brown Neurological Scholar Award from the American Neurological Association in 2004 and the Scientific Service Award from Autism Speaks in 2008.
 

News relating to Konopka et al, Nature 2009 paper:

Media related to the Geschwind lab article, "Human-Specific Transcriptional Regulation of CNS Development Genes by FOXP2", in the November 12th issue of Nature.

For a complete list of all articles relating to it please click here.

 

 

UCLA Medicine Magazine interviews Dr. Geschwind

image courtesy of Mitch Tobias, UCLA Medicine Magazine

Conversation: Dr. Daniel Geschwind, UCLA CART director.

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Featured Publications

Human-specific transcriptional regulation of CNS development genes by FOXP2

Volume 462 Number 7270 pp137-242

Konopka G, Bomar JM, Winden K, Coppola G, Jonsson ZO, Gao F, Peng S, Preuss TM, Wohlschlegel JA, Geschwind DH.

Speech, FOXP2 and the human–chimp divide

The transcription factor FOXP2 is the only gene so far to have been implicated in human speech, yet it differs very little from the chimpanzee equivalent.

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Neuroscience in the era of functional genomics and systems biology

Nature

Geschwind DH, Konopka G.

Advances in genetics and genomics have fuelled a revolution in discovery-based, or hypothesis-generating, research that provides a powerful complement to the more directly hypothesis-driven molecular, cellular and systems neuroscience. Genetic and functional genomic studies have already yielded important insights into neuronal diversity and function, as well as disease.

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